Z-score LORETA Neurofeedback as a Potential Therapy for Patients with Seizures and Refractory Epilepsy - Sci Forschen Inc.

Article Information

Article Type: Research Article

Citation: Koberda JL and Frey LC (2015) Z-score LORETA Neurofeedback as a Potential Therapy for Patients with Seizures and Refractory Epilepsy. Neurol Neurobiol, Volume1.1: doi http://dx.doi.org/10.16966/2379-7150.101

Copyright:© 2015 Koberda JL, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history:

 Received date: 05 January 2015.

 Accepted date: 26 January 2015.

 Published date: 31 January 2015.

#LORETA; #Z-score #NFB; #Epilepsy; #Seizures; #EEG; #QEEG


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Acute and Subacute Differential Gene Expression in Rat Midbrain Following Blast Exposure Compared to Mechanical Brain Trauma - Sci Forschen Inc.

Article Information

Article Type: Research Article

Citation: Svetlov SI, Prima V, Zhang Z , Curley KC, Kobeissy F, Moghieb A and Wang KKW (2015) Acute and Subacute Differential Gene Expression in Rat Midbrain Following Blast Exposure Compared to Mechanical Brain Trauma. Neurol Neurobiol, Volume1.1: http://dx.doi.org/10.16966/2379-7150.103

Copyright: © 2015 Svetlov SI. This is an openaccess article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history:

 Received date: 25 February, 2015.

 Accepted date: 03 March, 2015.

 Published date: 07 March, 2015.


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LORETA Z-score Neurofeedback in Patients with Medically Refractory Epilepsy - Sci Forschen Inc.

Article Information

Article Type: Research Article

Citation: Frey LC and Koberda JL (2015) LORETA Z-score Neurofeedback in Patients with Medically Refractory Epilepsy. Neurol Neurobiol, Volume1.1: http://dx.doi.org/10.16966/2379-7150.102

Copyright: © 2015 Frey LC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history:

 Received date: 15 January, 2015.

 Accepted date: 20 February, 2015.

 Published date: 27 February, 2015.


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The Third Brain in Autism: Opening the Doors to the Solution in Autism - Sci Forschen Inc.

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Article Type: Editorial

Citation: Rajalakshmi K (2015) The Third Brain in Autism: Opening the Doors to the Solution in Autism. Neurol Neurobiol, Volume1.1: http://dx.doi.org/10.16966/2379-7150.e002

Copyright: © 2015 Rajalakshmi K. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history:

 Received date: 7 March, 2015

 Accepted date:7 March, 2015

 Published date: 13 March, 2015


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Application of Z-score LORETA Neuro-feedback in Therapy of Epilepsy - Sci Forschen Inc.

Article Information

Article Type: Editorial

Citation: Koberda JL (2015) Application of Z-score LORETA Neuro-feedback in Therapy of Epilepsy. Neurol Neurobiol, Volume1.1:doi http://dx.doi.org/10.16966/2379-7150.e101

Copyright: © 2015 Koberda JL. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history:

 Received date: 26 January, 2015

 Accepted date:31 January, 2015

 Published date: 2 February, 2015

#Neurofeedback; #seizures; #epilepsy; #Z-score; #LORETA; #EEG; #QEEG

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Analysis Of Urinary Symptoms And Urodynamic Findings In Multiple Sclerosis Patients By Gender And Disease Subtype

Article Information

Article Type: Research Article

Citation: Cox L, Cameron AP, Wittman D, Papin JE, Mao-Draayer Y, et al. (2015) Analysis of Urinary Symptoms and Urodynamic Findings in Multiple Sclerosis Patients by Gender and Disease Subtype. J Neurol Neurobiol 1 (2): http://dx.doi.org/10.16966/2379-7150.105

Copyright:© 2015 Cox L, et al. This is an openaccess article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history:

 Received date: 22 April, 2015

 Accepted date: 29 April, 2015

 Published date: 05 May, 2015


Authors :

Cox L,      Cameron AP,      Wittman D,      Papin JE,      Mao-Draayer Y,      He C,      Clemens JQ,      Wei JT,      Sarma AV,      Stoffel JT*

Department of Urology, University of Michigan, 1500 E. Medical Center Dr. SPC 5330 Ann Arbor, MI, USA

*Corresponding author: John Stoffel, MD, University of Michigan,Department of Urology 1500 E. Medical Center Dr. SPC 5330 Ann Arbor, MI, USA, Tel: 48109-5330; E-mail: jstoffel@med.umich.edu

Abstract

Background: Although urinary symptoms are prevalent in multiple sclerosis (MS), there is little information whether bladder function differs by gender or disease subtype.

Objective: Differences in MS bladder function within subgroups were investigated by comparing female to male and relapsing remitting (RRMS) to secondary progressive (SPMS) patients.

Methods: We reviewed 118 MS patients referred for urologic evaluation between 2007 and 2012 and extracted demographic, questionnaire (AUASI, M-ISI), and urodynamic data. Variables were analyzed by gender and MS subtype, and a multivariable regression model was generated to adjust for age and gender

Results: The cohort consisted of83/35 female/male and 57/61RRMS/SPMS subjects. Urinary questionnaire and urodynamic findings were similar between genders, with the exception of higher maximum voiding pressures in males (p=0.003). RRMS patients reported more bothersome urinary symptoms compared to SPMS (AUASI21 vs. 15, p=0.004) and RRMS was independently associated with higher symptom scores on multivariable analysis (OR 17.1, p=0.008). There were no differences in urodynamic findings between subtypes.

Conclusions: Male and female MS patients had similar urinary symptom scores and urodynamic findings, with the exception of higher voiding pressures in males. RRMS patients reported significantly more severe urinary symptoms on AUASI, compared to SPMS, despite having similar urodynamic findings

Keywords
Multiple sclerosis; Neurogenic bladder; Urodynamic testing; Gender

Table 1: Characteristics by of Multiple Sclerosis Cohort Grouped by Disease Subtype


Table 2: Characteristics by of Multiple Sclerosis Cohort Grouped by Gender


Table 3:Characteristics by of Multiple Sclerosis Cohort Grouped by Disease Subtype


Table 4:Multivariable Analysis for Association between MS Subtype and Urinary Symptoms and Voiding PressuresAdjusted for Age and Gender

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Somatomotor and Behavioral Changes Following Traumatic Brain Injury

Article Information

Article Type: Research Article

Citation: Citation: Adams S, Condrey JA, Wen Tsai H, Svetlov SI, Prima V, Davenport PW (2015) Somatomotor and Behavioral Changes Following Traumatic Brain Injury. Neurol Neurobiol, Volume1.1: http://dx.doi.org/10.16966/2379-7150.104

Copyright: © 2015 Adams S et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication history:

 Received date: 26 February, 2015.

 Accepted date: 12 March, 2015.

 Published date: 17 March, 2015.

Authors :

 Sherry Adams ¹       Jillian A. Condrey ¹       Hsiu-Wen Tsai ¹       Stanislav I. Svetlov ²       Victor Prima ²       Paul W. Davenport ^1*    
1Department of Physiological Sciences, University of Florida, Gainesville FL, USA
²2Department of Medicine and Psychiatry, 1600 SW Archer Road, Box 100274, University of Florida, Gainesville, FL, USA

*Corresponding author: Dr. Paul W. Davenport, Department of Physiological Sciences, University of Florida, Gainesville, FL 32603, USA, Tel: 352-294-4025; Fax: 352-392-5145; E-mail: pdavenpo@ufl.edu

Abstract

Overpressurization blast (OB) exposure used to induce traumatic brain injury (TBI) in the rodent model can result in somatomotor and behavioral changes. Increased anxiety is evidenced after OB TBI in Dorsal and Frontal blast-wave exposed injured animals. Sustained impaired somatosensory functions occur after multiple OB injuries in Dorsal animals. Somatomotor function is impaired acutely but partially recovers after OB injury in Frontal animals. The Dorsal Group had reduction in risk-taking behavior in Group 1 (low pressure OB) and in total exploration in Group 2 (high pressure OB). The critical time point for somatosensory and somatomotor function impairment occurs at 24 hours post-OB injury with Group 1 demonstrating somatosensory and Group 2 demonstrating somatomotor deficits. The results suggest orientation and pressure magnitude have a significant impact on behavioral outcome measures following OB injuries as well as cumulative effects of repeated OB.



Table 1: Somatomotor evaluation after OB injury in sprague-dawley rats

Table 2: EPM evaluation after OB injury in sprague-dawley rats

Data expressed as mean ± SD. One-way ANOVA test followed by post hoc analysis by Tukey HSD method. *Denotes statistically significant change of values within group. Intergroup comparison one-way ANOVA test followed by post hoc analysis by Tukey HSD method.

Table 3: EPM evaluation after dorsal OB injury in sprague-dawley rats

Data expressed as mean ± SD. One-way ANOVA test followed by post hoc analysis by Tukey HSD method. *Denotes statistically significant change of values within group. Intergroup comparison one-way ANOVA test followed by post hoc analysis by Tukey HSD method.

Table 4: Somatomotor tests for sham, dorsal and frontal groups

Data expressed as mean ± SD. One-way ANOVA test followed by post hoc analysis by Tukey HSD method. Intergroup comparison one-way ANOVA test followed by post hoc analysis by Tukey HSD method.

Table 5: Somatomotor tests for dorsal groups 1 and 2

Data expressed as mean ± SD. One-way ANOVA test followed by post hoc analysis by Tukey HSD method. *Denotes statistically significant change from time value within group. Intergroup comparison one-way ANOVA test followed by post hoc analysis by Tukey HSD method.

Table 6: Somatosensory tests for sham, dorsal and frontal groups

Data expressed as mean ± SD. One-way ANOVA test followed by post hoc analysis by Tukey HSD method. *Denotes statistically significant change of values within group. Intergroup comparison one-way ANOVA test followed by post hoc analysis by Tukey HSD method.

Table 7: Somatosensory tests for dorsal groups 1 and 2

Data expressed as mean ± SD. One-way ANOVA test followed by post hoc analysis by Tukey HSD method. *Denotes statistically significant change from time value within group. Intergroup comparison one-way ANOVA test followed by post hoc analysis by Tukey HSD method.


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